Zero-point energy ,in conventional quantum physics, is the lowest possible energy that a quantum mechanical physical system may have; it is the energy of its ground state. All quantum mechanical systems undergo fluctuations even in their ground state and have an associated zero-point energy, a consequence of their wave-like nature. the origin of zero-point energy is the Heisenberg uncertainty principle, which states that, for a moving particle such as an electron, the more precisely one measures the position, the less exact the best possible measurement of its momentum (mass times velocity), and vice versa.. Zero-point energy is the energy that remains when all other energy is removed from a system. For example, liquid helium does not freeze under atmospheric pressure at any temperature because of its zero-point energy. The least possible uncertainty of position times momentum is specified by Planck's constant, h. A parallel uncertainty exists between measurements involving time and energy (and other so-called conjugate variables in quantum mechanics). This minimum uncertainty is not due to any correctable flaws in measurement, but rather reflects an intrinsic quantum fuzziness in the very nature of energy and matter springing from the wave nature of the various quantum fields. This leads to the concept of zero-point energy.
A harmonic oscillator is a useful conceptual tool in physics. Classically a harmonic oscillator, such as a mass on a spring, can always be brought to rest. However a quantum harmonic oscillator does not permit this. A residual motion will always remain due to the requirements of the Heisenberg uncertainty principle, resulting in a zero-point energy, equal to 1/2 hf, where f is the oscillation frequency.
Electromagnetic radiation can be pictured as waves flowing through space at the speed of light. The waves are not waves of anything substantive, but are ripples in a state of a theoretically defined field. However these waves do carry energy (and momentum), and each wave has a specific direction, frequency and polarization state. Each wave represents a ''propagating mode of the electromagnetic field.
The origin of the ZPE may be traced to the initial expansion of the cosmos. In the same way that energy is put into the fabric of a rubber band when it is stretched, or into the fabric of a balloon when it is inflated, the fabric of space also had energy invested into it at its original expansion. The process whereby the potential energy of the stretching is changed into the kinetic energy of the ZPE is explained in this paper. This process does not occur instantaneously but takes time to accomplish in the same way that a pan of food in the oven takes time to heat. As a consequence, the strength of the ZPE has built up with time. The form of the energy in the ZPE has been demonstrated to be primarily electromagnetic fields and/or waves of all wavelengths.
There is evidence that the universe expanded out to a maximum size and then became relatively static. Narliker and Arp demonstrated that a static cosmos was stable against collapse, but would oscillate slightly about its average position. As a consequence the energy per unit volume or energy density of the ZPE will oscillate about an average value once its maximum has been attained. This occurs because the ZPE energy per unit volume is slightly greater when the cosmos was at its minimum size, and slightly less at the cosmos maximum. It has been suggested that, as the strength of the Zero Point Energy (ZPE) was lower in the past, so too would be the Casimir effect and hence Van de Waal's forces. This has led to the suggestion of problems with surface tension, which leads to the question about what would happen to the shape of protein molecules which are dependent upon Van der Waal's forces.
As it turns out, the Casimir force per unit area is given by F/A = hc (pi)/(480a4). Here, "a" is the distance between the Casimir plates, or, what amounts to the same thing, the inter-molecular distance. For example, see the final equation here

 In this analysis, the only varying quantities are Planck's constant, h, and the speed of light, c. Planck's constant is directly proportional to the strength of the ZPE and the speed of light is inversely proportional to the ZPE strength. Thus the quantity "hc" is always invariant. The result is that the Casimir force remains unchanged with ZPE strength and, consequently, so does the Van der Waal's force. Hence there is no change in protein shape and there will be no change in surface tension in liquids. Although zero-point energy is usually regarded as a quantum phenomenon and a consequence of the Heisenberg uncertainty relationship, the existence of zero-point energy was inferred by Einstein, Planck, Nernst and others in the context of blackbody radiation prior to the discovery of quantum mechanics. Einstein and Otto Stern came close to deriving the blackbody function without assuming quantization but with the presence of zero-point energy. Nernst in particular claimed in 1916 that the universe was filled with zero-point energy. This line of investigation was abandoned with the advent of quantum mechanics, but the concept of zero-point energy soon reemerged with a quantum interpretation.Recent research has proven how these medicines work and is based on the “Zeropoint energy field which forms the basis of all matter – living and non living